Frontal alpha asymmetry: A potential biomarker of approach-withdrawal motivation towards pain.

ABSTRACT: Pain-related catastrophising is a maladaptive coping strategy known to have a strong influence on clinical pain outcomes and treatment efficacy. Notwithstanding, little is known about its neurophysiological correlates. There is evidence to suggest catastrophising is associated with resting-state EEG frontal alpha asymmetry (FAA) patterns reflective of greater relative right frontal activity, which is known to be linked to withdrawal motivation and avoidance of aversive stimuli. The present study aims to investigate whether such a relationship occurs in the situational context of experimental pain. A placebo intervention was also included to evaluate effects of a potential pain-relieving intervention on FAA. 35 participants, including both chronic pain patients and healthy subjects, complet

SUBMITTER: Silva-Passadouro B 

PROVIDER: S-EPMC9552005 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature