Association of Atrial Septal Aneurysm and Shunt Size With Stroke Recurrence and Benefit From Patent Foramen Ovale Closure.

ABSTRACT:

Importance

The Patent Foramen Ovale (PFO)-Associated Stroke Causal Likelihood classification system combines information regarding noncardiac patient features (vascular risk factors, infarct topography) and PFO features (shunt size and presence of atrial septal aneurysm [ASA]) to classify patients into 3 validated categories of responsiveness to treatment with PFO closure. However, the distinctive associations of shunt size and ASA, alone and in combination, have not been completely delineated.

Objective

To evaluate the association of PFO closure with stroke recurrence according to shunt size and/or the presence of an ASA.

Design, setting, and participants

Pooled individual patient data from 6 randomized clinical trials conducted from February 2000 to October 2017 tha

SUBMITTER: Mas JL 

PROVIDER: S-EPMC9552048 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature