Transcriptome profiling of lung immune responses potentially related to acute respiratory distress syndrome in forest musk deer.

ABSTRACT:

Background

Forest musk deer is an endangered species globally. The death of captive forest musk deer can be caused by certain respiratory system diseases. Acute respiratory distress syndrome (ARDS) is a huge threat to the life of forest muck deer that breed in our department.

Methods

Lung histopathologic analysis was conducted by hematoxylin and eosin (HE) staining. The lung gene changes triggered by ARDS were examined by RNA sequencing and related bioinformatics analysis in forest musk deer. The potential functions of unigenes were investigated by NR, SwissProt KOG, GO, and KEGG annotation analyses. Vital biological processes or pathways in ARDS were examined by GO and KEGG enrichment analyses.

Results

A total of 3265 unigenes were differentially expressed (|log

SUBMITTER: Tang J 

PROVIDER: S-EPMC9552132 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature