Electrophilic Trapping of Semibenzenes.

ABSTRACT: In this work, we demonstrate how allylative dearomatization of benzyl chlorides can provide direct access to a variety of semibenzenes. These scaffolds behave as highly reactive nucleophiles in the presence of carbocations. In addition, semibenzenes are susceptible to intramolecular rearrangements rendering a broad scope of functionalized arenes. An analysis of this new reactivity is reported, as well as the rationale behind the observed intramolecular reorganizations.

SUBMITTER: Boldrini C 

PROVIDER: S-EPMC9552181 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature