Ovarian metastases from ALK-positive lung adenocarcinoma: a case report and review of the literature

ABSTRACT:

Background

Ovarian metastasis is an extremely rare condition in patients with lung adenocarcinoma. Lung adenocarcinoma patients with ovarian metastases were difficult to distinguish from primary ovarian cancer. Anaplastic lymphoma kinase (ALK) gene rearrangement is only found in 3–7% of patients with lung cancer. It is worth noting that the incidence of lung cancer with ovarian metastasis is extremely low, however, ALK rearrangement is often reported in these cases. Here we reported a young woman, aged 23 years, with ALK-positive lung adenocarcinoma and ovarian metastasis.

Case Description

The patient underwent laparoscopic bilateral ovarian tumor resection after discovering an abdominal mass accidentally. A series of lung adenocarcinoma-specific immunohistochemical featu

SUBMITTER: Li H 

PROVIDER: S-EPMC9552264 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature