Impact of the national hepatitis B immunization program in China: a modeling study.

ABSTRACT:

Background

Elimination of hepatitis B virus (HBV) is a striking challenge for countries with high or moderate disease burden. Therefore, using China as a practical case to share experiences for similar countries may accelerate the achievement of the WHO 2030 target of 90% reduction in HBV-related incidence. We aim to evaluate the impact of national HBV immunization strategies in China; and the feasibility to achieve WHO 2030 targets under different scenarios.

Methods

We constructed an expanded Susceptible-Exposed-Infectious-Recovered (SEIR) model and decision tree-Markov model to estimate the epidemic of HBV in China, assess the feasibility of 2030 Elimination Goals through the projections and conduct the economic analysis. Least square method was used to calibrate the expan

SUBMITTER: Liu Z 

PROVIDER: S-EPMC9552421 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature