Ontology highlight
ABSTRACT:
SUBMITTER: Guevara-Garcia A
PROVIDER: S-EPMC9552562 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Guevara-Garcia Amaris A Fourel Laure L Bourrin-Reynard Ingrid I Sales Adria A Oddou Christiane C Pezet Mylène M Rossier Olivier O Machillot Paul P Chaar Line L Bouin Anne-Pascale AP Giannone Gregory G Destaing Olivier O Picart Catherine C Albiges-Rizo Corinne C
The Journal of cell biology 20221007 12
The spatial organization of cell-surface receptors is fundamental for the coordination of biological responses to physical and biochemical cues of the extracellular matrix. How serine/threonine kinase receptors, ALK3-BMPRII, cooperate with integrins upon BMP2 to drive cell migration is unknown. Whether the dynamics between integrins and BMP receptors intertwine in space and time to guide adhesive processes is yet to be elucidated. We found that BMP2 stimulation controls the spatial organization ...[more]