Study on the interaction between different pathogens of Hand, foot and mouth disease in five regions of China

ABSTRACT:

Objectives

This study aims to explore the interaction of different pathogens in Hand, foot and mouth disease (HFMD) by using a mathematical epidemiological model and the reported data in five regions of China.

Methods

A cross-regional dataset of reported HFMD cases was built from four provinces (Fujian Province, Jiangsu province, Hunan Province, and Jilin Province) and one municipality (Chongqing Municipality) in China. The subtypes of the pathogens of HFMD, including Coxsackievirus A16 (CV-A16), enteroviruses A71 (EV-A71), and other enteroviruses (Others), were included in the data. A mathematical model was developed to fit the data. The effective reproduction number (Reff) was calculated to quantify the transmissibility of the pathogens.

Results

In total, 3,336

SUBMITTER: Yang Z 

PROVIDER: S-EPMC9552780 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature