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Pathogen evolution during vaccination campaigns.


ABSTRACT: Following the initiation of the unprecedented global vaccination campaign against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), attention has now turned to the potential impact of this large-scale intervention on the evolution of the virus. In this Essay, we summarize what is currently known about pathogen evolution in the context of immune priming (including vaccination) from research on other pathogen species, with an eye towards the future evolution of SARS-CoV-2.

SUBMITTER: Day T 

PROVIDER: S-EPMC9553060 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

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Pathogen evolution during vaccination campaigns.

Day Troy T   Kennedy David A DA   Read Andrew F AF   Gandon Sylvain S  

PLoS biology 20220923 9


Following the initiation of the unprecedented global vaccination campaign against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), attention has now turned to the potential impact of this large-scale intervention on the evolution of the virus. In this Essay, we summarize what is currently known about pathogen evolution in the context of immune priming (including vaccination) from research on other pathogen species, with an eye towards the future evolution of SARS-CoV-2. ...[more]

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