The Association Between Peripheral Oxytocin Levels and Depressive Symptoms in People With HIV.

ABSTRACT:

Objective

Depression is common in people with HIV (PWH), yet little is known about the mechanisms contributing to depressive symptoms in PWH. Previous research across a range of populations has suggested a relationship between the neuropeptide oxytocin and depressive symptoms, with variable directionality. This article investigated the association between peripheral oxytocin levels and depressive symptoms in PWH.

Methods

Unextracted oxytocin serum concentrations were assayed in 79 PWH (44% female, mean age = 34.35 [8.5], mean body mass index = 25.69 [5.46], mean CD4 = 516.60 [271.15]) who also completed the Center for Epidemiologic Studies Depression Scale (CES-D). CES-D items were evaluated in an exploratory factor analysis (EFA), and the relationships between oxytocin, tot

SUBMITTER: Shortell DD 

PROVIDER: S-EPMC9553265 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature