Early Life Trauma and Social Processing in HIV: The Role of Neuroendocrine Factors and Inflammation.

ABSTRACT:

Objective

Early life trauma (ELT) and HIV are associated with social processing deficits. In people with HIV (PWH), we examined whether facial emotion identification accuracy differs by ELT and whether neuroendocrine factors including cortisol, oxytocin (OT), and arginine vasopressin, and/or immune system measures play a role in the ELT-performance association.

Methods

We used secondary data from the placebo condition of a pharmacologic challenge study in PWH. Presence of ELT was measured with the Childhood Trauma Questionnaire (at least moderate experiences of sexual, physical, and/or emotional abuse). Social processing was measured with the Facial Emotion Perception Test (FEPT). Salivary immune system measures and cortisol were sampled across a 5-hour study session. Blood

SUBMITTER: Rubin LH 

PROVIDER: S-EPMC9553269 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature