The assessment of left ventricular mechanical dyssynchrony from gated ^99mTc-tetrofosmin SPECT and gated ¹⁸F-FDG PET by QGS: a comparative study.

ABSTRACT:

Background

Due to partly conflicting studies, further research is warranted with the QGS software package, with regard to the performance of gated FDG PET phase analysis as compared to gated MPS as well as the establishment of possible cut-off values for FDG PET to define dyssynchrony.

Methods

Gated MPS and gated FDG PET datasets of 93 patients were analyzed with the QGS software. BW, Phase SD, and Entropy were calculated and compared between the methods. The performance of gated PET to identify dyssynchrony was measured against SPECT as reference standard. ROC analysis was performed to identify the best discriminator of dyssynchrony and to define cut-off values.

Results

BW and Phase SD differed significantly between the SPECT and PET. There was no significant differe

SUBMITTER: Lehner S 

PROVIDER: S-EPMC9553767 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature