Perceptions of causal attribution and attitudes to genetic testing among people with schizophrenia and their first-degree relatives.

ABSTRACT: Rapid advances in the genetics of psychiatric disorders mean that diagnostic and predictive genetic testing for schizophrenia risk may one day be a reality. This study examined how causal attributions for schizophrenia contribute to interest in a hypothetical genetic test. People with schizophrenia and first-degree relatives of people with schizophrenia were recruited through a schizophrenia research bank and mental health organisation. Semi-structured telephone interviews were conducted with 13 individuals with schizophrenia and 8 first-degree relatives. Transcripts were subjected to a qualitative analysis using the thematic analysis framework. Five themes were developed: (i) "It is like a cocktail", with most participants aware that both genetic and environmental factors contributed to c

SUBMITTER: Cullen MBR 

PROVIDER: S-EPMC9553941 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature