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Patient attrition in Molecular Tumour Boards: a systematic review.


ABSTRACT:

Background

Molecular Tumour Boards (MTBs) were created with the purpose of supporting clinical decision-making within precision medicine. Though in use globally, reporting on these meetings often focuses on the small percentages of patients that receive treatment via this process and are less likely to report on, and assess, patients who do not receive treatment.

Methods

A literature review was performed to understand patient attrition within MTBs and barriers to patients receiving treatment. A total of 51 papers were reviewed spanning a 6-year period from 11 different countries.

Results

In total, 20% of patients received treatment through the MTB process. Of those that did not receive treatment, the main reasons were no mutations identified (27%), no actionable mutat

SUBMITTER: Frost H 

PROVIDER: S-EPMC9553981 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature