Case report: IgG4-related intracranial lesions mimicking multiple sclerosis in a 14-year-old girl.

ABSTRACT:

Objectives

IgG4-related disease (IgG4-RD) is distinguished by the infiltration of IgG4-positive plasma cells in a variety of tissues and organs. Even so, central nervous system lesions associated with IgG4-RD are scarce. We present a case of IgG4-related brain parenchymal lesions that mimics multiple sclerosis in a young girl.

Methods

The patient was followed by our neurology and rheumatology teams. Clinical information was recorded, and the brain was screened using magnetic resonance imaging (MRI). During follow-up, we examined serum IgE, IgG and IgG4 and lymph node biopsy.

Results

Here, we presented details of a 14-year-old Chinese girl suffering from diplopia, left eyelid ptosis, right facial numbness, and right lower limb weakness admitted to our institute. Brain

SUBMITTER: Qing P 

PROVIDER: S-EPMC9554464 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature