Associations of Early-Life Exposure to Submicron Particulate Matter With Childhood Asthma and Wheeze in China.

ABSTRACT:

Importance

Exposure to particulate matter (PM) has been associated with childhood asthma and wheeze. However, the specific associations between asthma and PM with an aerodynamic equivalent diameter of 1 μm or less (ie, PM1), which is a contributor to PM2.5 and potentially more toxic than PM2.5, remain unclear.

Objective

To investigate the association of early-life (prenatal and first year) exposure to size-segregated PM, including PM1, PM1-2.5, PM2.5, PM2.5-10, and PM10, with childhood asthma and wheeze.

Design, setting, and participants

This cross-sectional study was based on a questionnaire administered between June 2019 and June 2020 to caregivers of children aged 3 to 6 years in 7 Chinese cities (Wuhan, Changsha, Taiyuan, Nanjing, Shanghai, Chongqing, and Urumqi)

SUBMITTER: Wu C 

PROVIDER: S-EPMC9554703 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature