Strategies for post-cardiac surgery acute kidney injury prevention: A network meta-analysis of randomized controlled trials.

ABSTRACT:

Objects

Cardiac surgery is associated with acute kidney injury (AKI). However, the effects of various pharmacological and non-pharmacological strategies for AKI prevention have not been thoroughly investigated, and their effectiveness in preventing AKI-related adverse outcomes has not been systematically evaluated.

Methods

Studies from PubMed, Embase, and Medline and registered trials from published through December 2021 that evaluated strategies for preventing post-cardiac surgery AKI were identified. The effectiveness of these strategies was assessed through a network meta-analysis (NMA). The secondary outcomes were prevention of dialysis-requiring AKI, mortality, intensive care unit (ICU) length of stay (LOS), and hospital LOS. The interventions were ranked using the P

SUBMITTER: Chen JJ 

PROVIDER: S-EPMC9555275 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature