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ABSTRACT: Objectives
Head-elevated body positioning, a default clinical practice, predictably increases end-expiratory transpulmonary pressure and aerated lung volume. In acute respiratory distress syndrome (ARDS), however, the net effect of such vertical inclination on tidal mechanics depends upon whether lung recruitment or overdistension predominates. We hypothesized that in moderate to severe ARDS, bed inclination toward vertical unloads the chest wall but adversely affects overall respiratory system compliance (C rs ).Design
Prospective physiologic study.Setting
Two medical ICUs in the United States.Patients
Seventeen patients with ARDS, predominantly moderate to severe.Intervention
Patients were ventilated passively by volume control. We measured airway
SUBMITTER: Selickman J
PROVIDER: S-EPMC9555829 | biostudies-literature | 2022 Nov
REPOSITORIES: biostudies-literature