Flexing the principal gradient of the cerebral cortex to suit changing semantic task demands.

ABSTRACT: Understanding how thought emerges from the topographical structure of the cerebral cortex is a primary goal of cognitive neuroscience. Recent work has revealed a principal gradient of intrinsic connectivity capturing the separation of sensory-motor cortex from transmodal regions of the default mode network (DMN); this is thought to facilitate memory-guided cognition. However, studies have not explored how this dimension of connectivity changes when conceptual retrieval is controlled to suit the context. We used gradient decomposition of informational connectivity in a semantic association task to establish how the similarity in connectivity across brain regions changes during familiar and more original patterns of retrieval. Multivoxel activation patterns at opposite ends of the principal

SUBMITTER: Gao Z 

PROVIDER: S-EPMC9555860 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature