Disordered eating in early childhood: DRD4 and DAT1 gene polymorphisms and quality of mother-child interaction.

ABSTRACT:

Purpose

Eating disturbances are complex heritable conditions that can be influenced by both genetic and environmental factors but are poorly studied in early development. The aim of this research was to investigate the association of genetic polymorphisms within dopaminergic pathways with early feeding problems.

Methods

We analyzed the presence of VNTR polymorphisms of DRD4 (rs1805186) and DAT1 (rs28363170) in overeating (N = 45), undereating (N = 48) and control (N = 44) young children. We also assessed presence of externalizing, internalizing and dysregulation symptoms by the Child Behavior Checklist and quality of mother-child interactions during feeding by the Italian adaptation of the Scale for the Assessment of Feeding Interaction, respectively.

Results

Both pol

SUBMITTER: Pascale E 

PROVIDER: S-EPMC9556347 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature