Five material tissue decomposition by dual energy computed tomography.

ABSTRACT: The separation of mixtures of substances into their individual components plays an important role in many areas of science. In medical imaging, one method is the established analysis using dual-energy computed tomography. However, when analyzing mixtures consisting of more than three individual basis materials, a physical limit is reached that no longer allows this standard analysis. In addition, the X-ray attenuation coefficients of chemically complicated basis materials may not be known and also cannot be determined by other or previous analyses. To address these issues, we developed a novel theoretical approach and algorithm and tested it on samples prepared in the laboratory as well as on ex-vivo medical samples. This method allowed both five-material decomposition and determination or

SUBMITTER: Lochschmidt ME 

PROVIDER: S-EPMC9556609 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature