Combined Donor-Recipient Obesity and the Risk of Graft Loss After Kidney Transplantation.

ABSTRACT: Background: As the prevalence of obesity increases globally, appreciating the effect of donor and recipient (DR) obesity on graft outcomes is of increasing importance. Methods: In a cohort of adult, kidney transplant recipients (2000-2017) identified using the SRTR, we used Cox proportional hazards models to examine the association between DR obesity pairing (body mass index (BMI) >30 kg/m²), and death-censored graft loss (DCGL) or all-cause graft loss, and logistic regression to examine risk of delayed graft function (DGF) and ≤30 days graft loss. We also explored the association of DR weight mismatch (>30 kg, 10-30 kg (D>R; DResults: Relative to non-obese DR, obese DR were highes

SUBMITTER: Jarrar F 

PROVIDER: S-EPMC9556700 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature