External validation and clinical application of the predictive model for severe hypoglycemia.

ABSTRACT:

Objective

An internally validated, one-year risk prediction model for severe hypoglycemia (SH) in type 2 diabetes was evaluated in a general hospital setting to externally verify and validate its performance.

Research design and methods

Between December 2017 to December 2019, 2,645 adult patients with type 2 diabetes who visited the diabetes center were enrolled. The receiver operating characteristics curve and Harrell C-statistics were compared to identify the discrimination of the model. The predicted and actual incidence of SH for one year in the development and validation cohorts were compared by ranking participants by deciles of predicted risk.

Results

The concordance index was 0.878 in the external validation cohort. The sensitivity and specificity of the predi

SUBMITTER: Yun JS 

PROVIDER: S-EPMC9556834 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature