Effect of hybrid immunity, school reopening, and the Omicron variant on trajectory of COVID-19 epidemic in India: A modelling study.

ABSTRACT:

Background

The course of the COVID-19 pandemic has been driven by several dynamic behavioral, immunological, and viral factors. We used mathematical modeling to explore how the concurrent reopening of schools, increasing levels of hybrid immunity, and the emergence of the Omicron variant affected the trajectory of the pandemic in India, using Andhra Pradesh (pop: 53 million) as an exemplar Indian state.

Methods

We constructed an age- and contact-structured compartmental model that allows for individuals to proceed through various states depending on whether they have received zero, one, or two doses of the COVID-19 vaccine. We calibrated our model using results from another model (ie, INDSCI-SIM) as well as available context-specific serosurvey data. The introduction of the

SUBMITTER: Mozaffer F 

PROVIDER: S-EPMC9556909 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature