Detecting glaucoma from multi-modal data using probabilistic deep learning.

ABSTRACT:

Objective

To assess the accuracy of probabilistic deep learning models to discriminate normal eyes and eyes with glaucoma from fundus photographs and visual fields.

Design

Algorithm development for discriminating normal and glaucoma eyes using data from multicenter, cross-sectional, case-control study.

Subjects and participants

Fundus photograph and visual field data from 1,655 eyes of 929 normal and glaucoma subjects to develop and test deep learning models and an independent group of 196 eyes of 98 normal and glaucoma patients to validate deep learning models.

Main outcome measures

Accuracy and area under the receiver-operating characteristic curve (AUC).

Methods

Fundus photographs and OCT images were carefully examined by clinicians to identify glauco

SUBMITTER: Huang X 

PROVIDER: S-EPMC9556968 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature