Increased variability of mean arterial pressure is associated with increased risk of short-term mortality in intensive care unit: A retrospective study.

ABSTRACT:

Background

In intensive care unit (ICU), what thresholds of MAP variability are effective in distinguishing low- and high-risk patients for short-term mortality (in-hospital and 28-day) remains unclear.

Methods

Fifteen thousand five hundred sixty adult subjects admitted to ICU at Beth Israel Deaconess Medical Center (Boston, USA) between 2001 and 2012 were included in this retrospective study from MIMIC-III database. MAP within the first 24 h after admission were collected. Quantiles of MAP variability from 10% to 90% with 10% increasement each were considered to divide study participants into two groups, either having coefficients of variation of MAP greater or less than the given threshold. The threshold of MAP variability was identified by maximizing the odds ratio associ

SUBMITTER: Yao J 

PROVIDER: S-EPMC9557059 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature