Prognostic impact of incident left ventricular systolic dysfunction after myocardial infarction.

ABSTRACT:

Introduction

We sought to investigate the prognostic impact of incident left ventricular (LV) systolic dysfunction at the chronic phase of acute myocardial infarction (AMI).

Materials and methods

Among 2,266 consecutive patients admitted for AMI, 1,330 patients with LV ejection fraction (LVEF) ≥ 40% during hospitalization who had LVEF data at 6 months after AMI were analyzed. Patients were divided into three subgroups based on LVEF at 6 months: reduced-LVEF (<40%), mid-range-LVEF (≥ 40% and < 50%) and preserved-LVEF (≥ 50%). Occurrence of a composite of hospitalization for heart failure or cardiovascular death after 6 months of AMI was the primary endpoint. The prognostic impact of LVEF at 6 months was assessed with a multivariate-adjusted Cox model.

Results

Overall,

SUBMITTER: Yoshioka G 

PROVIDER: S-EPMC9557083 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature