Effects of aging on cognitive and brain inter-network integration patterns underlying usual and dual-task gait performance.

ABSTRACT:

Introduction

Aging affects the interplay between cognition and gait performance. Neuroimaging studies reported associations between gait performance and structural measures; however, functional connectivity (FC) analysis of imaging data can help to identify dynamic neural mechanisms underlying optimal performance. Here, we investigated the effects on divergent cognitive and inter-network FC patterns underlying gait performance during usual (UW) and dual-task (DT) walking.

Methods

A total of 115 community-dwelling, healthy participants between 20 and 80 years were enrolled. All participants underwent comprehensive cognitive and gait assessments in two conditions and resting state functional MRI (fMRI) scans. Inter-network FC from motor-related to 6 primary cognitive networks

SUBMITTER: Droby A 

PROVIDER: S-EPMC9557358 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature