Association between indoor residual spraying and pregnancy outcomes: a quasi-experimental study from Uganda.

ABSTRACT:

Background

Malaria is a risk factor for adverse pregnancy outcomes. Indoor residual spraying with insecticide (IRS) reduces malaria infections, yet the effects of IRS on pregnancy outcomes are not well established. We evaluated the impact of a large-scale IRS campaign on pregnancy outcomes in Eastern Uganda.

Methods

Birth records (n = 59 992) were obtained from routine surveillance data at 25 health facilities from five districts that were part of the IRS campaign and six neighbouring control districts ∼27 months before and ∼24 months after the start of the campaign (January 2013-May 2017). Campaign effects on low birthweight (LBW) and stillbirth incidence were estimated using the matrix completion method (MC-NNM), a machine-learning approach to estimating potential outcomes

SUBMITTER: Roh ME 

PROVIDER: S-EPMC9557839 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature