Parental fecundability and neurodevelopmental delays and difficulties in offspring.

ABSTRACT:

Background

Impaired neurodevelopment is reported among children conceived by assisted reproductive technologies (ART). However, this might be explained by conditions underlying parental subfecundity, rather than the ART procedure.

Methods

We examined associations of parental time-to-pregnancy (TTP) and conception by ART with neurodevelopmental traits up to 8 years of age, including motor and language skills, social delays and difficulties, and inattention-hyperactivity, among 92 142 singletons participating in the Norwegian Mother, Father and Child Cohort Study (MoBa). Mothers reported TTP and neurodevelopmental traits through questionnaires. Mean differences in standardized neurodevelopmental traits were estimated using linear regression, adjusting for maternal age, parity,

SUBMITTER: Magnus MC 

PROVIDER: S-EPMC9557840 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature