Salvage transjugular intrahepatic portosystemic shunt in patients with cirrhosis and refractory variceal bleeding: A systematic review with meta-analysis.

ABSTRACT:

Background

Transjugular intrahepatic portosystemic shunt (TIPS) may be used as a salvage treatment in patients with cirrhosis and refractory variceal bleeding.

Aim

To synthesize the available evidence on the efficacy of TIPS in patients with cirrhosis and refractory variceal bleeding.

Methods

Meta-analysis of trials evaluating TIPS in patients with cirrhosis and refractory variceal bleeding, including subgroup analysis to assess the impact of recent changes in the management of variceal bleeding (i.e., the use of Polytetrafluoroethylene-covered TIPS and the availability of pre-emptive TIPS as a first-line treatment for acute variceal bleeding).

Results

Twenty-three studies with 1430 patients were included. The pooled estimate rates were 0.33 (95% CI = 0.29-0.37

SUBMITTER: Weichselbaum L 

PROVIDER: S-EPMC9557966 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature