Aetiology and Potential Animal Exposure in Central Nervous System Infections in Vietnam.

ABSTRACT: An estimated 73% of emerging infections are zoonotic in origin, with animal contact and encroachment on their habitats increasing the risk of spill-over events. In Vietnam, close exposure to a wide range of animals and animal products can lead to acquisition of zoonotic pathogens, a number of which cause central nervous system (CNS) infections. However, studies show the aetiology of CNS infections remains unknown in around half of cases. We used samples and data from hospitalised patients with CNS infections, enrolled into the Vietnam Initiative on Zoonotic Infections multicentre study, to determine the association between aetiology and animal contact including those in whom the cause was unknown. Among 933 patients, a pathogen or an antibody response to it was identified in 291 (31.2%, 95

SUBMITTER: Brindle HE 

PROVIDER: S-EPMC9558024 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature