Fully automated detection and localization of clinically significant prostate cancer on MR images using a cascaded convolutional neural network.

ABSTRACT:

Purpose

To develop a cascaded deep learning model trained with apparent diffusion coefficient (ADC) and T2-weighted imaging (T2WI) for fully automated detection and localization of clinically significant prostate cancer (csPCa).

Methods

This retrospective study included 347 consecutive patients (235 csPCa, 112 non-csPCa) with high-quality prostate MRI data, which were randomly selected for training, validation, and testing. The ground truth was obtained using manual csPCa lesion segmentation, according to pathological results. The proposed cascaded model based on Res-UNet takes prostate MR images (T2WI+ADC or only ADC) as inputs and automatically segments the whole prostate gland, the anatomic zones, and the csPCa region step by step. The performance of the models was evalua

SUBMITTER: Zhu L 

PROVIDER: S-EPMC9558117 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature