Behavioral effects in disorders of consciousness following transcranial direct current stimulation: A systematic review and individual patient data meta-analysis of randomized clinical trials.

ABSTRACT:

Background

In patients with Disorders of Consciousness (DoC), recent evidence suggests that transcranial direct current stimulation (tDCS) can be a promising intervention for them. However, there has been little agreement on the treatment effect and the optimal treatment strategy for the tDCS in patients with DoC.

Objective

In this meta-analysis of individual patient data (IPD), we assess whether tDCS could improve DoC patients' behavioral performance. We also determine whether these treatment effects could be modified by patient characteristics or tDCS protocol.

Methods

We searched PubMed, Embase, and the Cochrane Central Register of Controlled Trials until 7 April 2022 using the terms "persistent vegetative state," "minimally conscious state," "disorder of conscious

SUBMITTER: Xu Z 

PROVIDER: S-EPMC9558708 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature