Follow-up of young adult monozygotic twins after simultaneous critical coronavirus disease 2019: A case report.

ABSTRACT:

Background

The influence of the host genome on coronavirus disease 2019 (COVID-19) susceptibility and severity is supported by reports on monozygotic (MZ) twins where both were infected simultaneously with similar disease outcomes, including several who died due to the SARS-CoV-2 infection within days apart. However, successive exposures to pathogens throughout life along with other environmental factors make the immune response unique for each individual, even among MZ twins.

Case presentation and methods

Here we report a case of a young adult monozygotic twin pair, who caught attention since both presented simultaneously severe COVID-19 with the need for oxygen support despite age and good health conditions. One of the twins, who spent more time hospitalized, reported symp

SUBMITTER: de Castro MV 

PROVIDER: S-EPMC9558815 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature