Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states.

ABSTRACT: Saliva is crucial for lubricating the mouth and aiding in food digestion. However, the occurrence of oral dysfunction, such as xerostomia, dysphagia or oral infection can markedly reduce the quality of life of affected individuals. The major salivary glands include the submandibular gland (SMG), and sublingual and parotid glands; they are the larger glands in mammals that produce the majority of the saliva. The SMG serves as an effective model for the study of branching morphogenesis and functional regeneration. In order to better understand the key dynamic gene expression patterns during salivary gland development and functional regeneration, it is crucial to search for a panel of reliable reference genes. The present study thus aimed to identify superior reference genes to normalize gene

SUBMITTER: Liu H 

PROVIDER: S-EPMC9559174 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature