Biological and Clinical Aspects of Metastatic Spinal Tumors.

ABSTRACT: Spine metastases are a common life-threatening complication of advanced-stage malignancies and often result in poor prognosis. Symptomatic spine metastases develop in the course of about 10% of malignant neoplasms. Therefore, it is essential for contemporary medicine to understand metastatic processes in order to find appropriate, targeted therapeutic options. Thanks to continuous research, there appears more and more detailed knowledge about cancer and metastasis, but these transformations are extremely complicated, e.g., due to the complexity of reactions, the variety of places where they occur, or the participation of both tumor cells and host cells in these transitions. The right target points in tumor metastasis mechanisms are still being researched; that will help us in the proper di

SUBMITTER: Litak J 

PROVIDER: S-EPMC9559304 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature