Effect of Toll-Like Receptor 7 Gene Polymorphism and ABO Blood Groups on the Severity of COVID-19 Patients.

ABSTRACT:

Background

The most current threat to global health is the continuous spread of a respiratory disease known as COVID-19 Disease 2019 in recent years. COVID-19 was recognized in December 2019. It was quickly determined that a novel COVID-19 virus, which is structurally linked to the virus that causes the severe acute respiratory syndrome, was to cause (SARS).

Objective

The aim of this study is to investigate the presence of effect between the rs179008 (A/T) SNP polymorphism in TLR7 gene and blood group on the severity of COVID-19.

Methods

The study included 90 patients divided into three groups mild, moderate, severe, and experimental research work was conducted during the period of sample collection extended from November 2021 to February, PCR-RFLP technique was used

SUBMITTER: Al-Tamimi ZHD 

PROVIDER: S-EPMC9559784 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature