Systemic Factors Associated with a Thinner Choroid in Preterm Infants.

ABSTRACT:

Purpose

To identify systemic health factors associated with a thinner choroid, which has been hypothesized as a cause of poor visual outcomes in low-birth weight infants.

Design

The prospective, observational Study of Eye Imaging in Preterm Infants (BabySTEPS) enrolled infants recommended for retinopathy of prematurity screening based on the American Association of Pediatrics guidelines.

Participants

Infants who underwent imaging with investigational handheld OCT at 36 ± 1 weeks' postmenstrual age (PMA) as part of BabySTEPS.

Methods

Average choroidal thickness was measured across the central subfoveal 1 mm. We concurrently collected maternal and infant clinical health data. Univariate and multivariate linear regression analyses were performed to evaluate factor

SUBMITTER: Michalak SM 

PROVIDER: S-EPMC9559969 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature