Longitudinal Evaluation of Visual Function Impairments in Early and Intermediate Age-Related Macular Degeneration Patients.

ABSTRACT:

Purpose

To evaluate visual function (VF) changes in early and intermediate age-related macular degeneration (eAMD and iAMD) over 24 months.

Design

Prospective, observational natural history study.

Participants

Participants were enrolled at the Duke Eye Center.

Methods

A total of 101 subjects (33 with eAMD, 47 with iAMD, and 21 normal controls) were recruited. Visual function (VF) tests included best-corrected visual acuity (BCVA), low- luminance visual acuity (LLVA), microperimetry (MP), cone contrast tests (CCTs), and dark adaptation (DA). Mixed-effect model repeated measures based on absolute values and change from baseline identified VF tests differentiating AMD from controls and revealing longitudinal VF decline when controlling for covariates (baseline val

SUBMITTER: Lad EM 

PROVIDER: S-EPMC9559970 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature