Effects of vitamin D supplementation during pregnancy on bone health and offspring growth: A systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Background

Whether vitamin D supplementation during pregnancy is beneficial to bone health and offspring growth remains controversial. Moreover, there is no universal agreement regarding the appropriate dose and the time of commencement of vitamin D supplementation during pregnancy.

Objective

We aimed to systematically review the effects of vitamin D supplementation during pregnancy on bone development and offspring growth.

Methods

A literature search for randomized controlled trials (RCTs) was performed in 7 electronic databases to identify relevant studies about the effects of vitamin D supplementation during pregnancy on bone development and offspring growth from inception to May 22, 2022. A Cochrane Risk Assessment Tool was used for quality assessment. Vitamin D s

SUBMITTER: Luo T 

PROVIDER: S-EPMC9560143 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature