Safety of paclitaxel-coated devices in the femoropopliteal arteries: A systematic review and meta-analysis.

ABSTRACT:

Background

Clinical benefit of paclitaxel-coated devices for patients with peripheral arterial disease has been confirmed in randomized controlled trials (RCTs). A meta-analysis published in 2018 identified late mortality risk over a long follow-up period due to use of paclitaxel-coated devices in the femoropopliteal arteries, which caused enormous controversy and debates globally. This study aims to further evaluate the safety of paclitaxel-coated devices by incorporating the most recently published data.

Methods

We searched for candidate studies in PubMed (MEDLINE), Scopus, EMBASE (Ovid) online databases, government web archives and international cardiovascular conferences. Safety endpoints of interest included all-cause mortality rates at one, two and five years and the r

SUBMITTER: Zhang C 

PROVIDER: S-EPMC9560511 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature