Specification of the endocrine primordia controlling insect moulting and metamorphosis by the JAK/STAT signalling pathway.

ABSTRACT: The corpora allata and the prothoracic glands control moulting and metamorphosis in insects. These endocrine glands are specified in the maxillary and labial segments at positions homologous to those forming the trachea in more posterior segments. Glands and trachea can be homeotically transformed into each other suggesting that all three evolved from a metamerically repeated organ that diverged to form glands in the head and respiratory organs in the trunk. While much is known about tracheal specification, there is limited information about corpora allata and prothorathic gland specification. Here we show that the expression of a key regulator of early gland development, the snail gene, is controlled by the Dfd and Scr Hox genes and by the Hedgehog and Wnt signalling pathways that induce

SUBMITTER: Garcia-Ferres M 

PROVIDER: S-EPMC9560620 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature