Alterations in the Choroidal Sublayers in Relationship to Severity and Progression of Diabetic Retinopathy: A Swept-Source OCT Study.

ABSTRACT:

Purpose

To examine the association of baseline choroidal sublayers metrics with the risk of diabetic retinopathy (DR) progression over 2 years, with adjustment for confounding factors that affect choroidal measurements.

Design

Prospective, observational cohort study.

Participants

One hundred three eyes from 62 patients with diabetes mellitus (DM).

Methods

Patients were followed up at 6-month intervals for at least 2 years. Choroidal metrics including choroidal area, choroidal thickness (CT), and choroidal vascularity index were measured for both (1) the choriocapillaris plus Sattler's layer and (2) the Haller's layer within the subfoveal and parafoveal region. Cox proportional models were constructed to estimate the relationship between baseline choroidal metri

SUBMITTER: Kung EWT 

PROVIDER: S-EPMC9560641 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature