The association of patient age with postoperative morbidity and mortality following resection of intracranial tumors.

ABSTRACT:

Introduction

The postoperative functional status of patients with intracranial tumors is influenced by patient-specific factors, including age.

Research question

This study aimed to elucidate the association between age and postoperative morbidity or mortality following the resection of brain tumors.

Material and methods

A multicenter database was retrospectively reviewed. Functional status was assessed before and 3-6 months after tumor resection by the Karnofsky Performance Scale (KPS). Uni- and multivariable linear regression were used to estimate the association of age with postoperative change in KPS. Logistic regression models for a ≥10-point decline in KPS or mortality were built for patients ≥75 years.

Results

The total sample of 4864 patients had a mean

SUBMITTER: Yang Y 

PROVIDER: S-EPMC9560674 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature