A highly selective response to food in human visual cortex revealed by hypothesis-free voxel decomposition.

ABSTRACT: Prior work has identified cortical regions selectively responsive to specific categories of visual stimuli. However, this hypothesis-driven work cannot reveal how prominent these category selectivities are in the overall functional organization of the visual cortex, or what others might exist that scientists have not thought to look for. Furthermore, standard voxel-wise tests cannot detect distinct neural selectivities that coexist within voxels. To overcome these limitations, we used data-driven voxel decomposition methods to identify the main components underlying fMRI responses to thousands of complex photographic images. Our hypothesis-neutral analysis rediscovered components selective for faces, places, bodies, and words, validating our method and showing that these selectivities are

SUBMITTER: Khosla M 

PROVIDER: S-EPMC9561032 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature