Light at night and the risk of breast cancer: Findings from the Sister study.

ABSTRACT:

Background

Light at night (LAN) may alter estrogen regulation through circadian disruption. High levels of outdoor LAN may increase breast cancer risk, but studies have largely not considered possible residual confounding from correlated environmental exposures. We evaluated the association between indoor and outdoor LAN and incident breast cancer.

Methods

In 47,145 participants in the prospective Sister Study cohort living in the contiguous U.S., exposure to outdoor LAN was determined using satellite-measured residential data and indoor LAN was self-reported (light/TV on, light from outside the room, nightlight, no light). We used Cox proportional hazards models to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for the associations between outdoor and indo

SUBMITTER: Sweeney MR 

PROVIDER: S-EPMC9561075 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature