Disrupted functional connectivity patterns of the left inferior frontal gyrus subregions in benign childhood epilepsy with centrotemporal spikes.

ABSTRACT:

Background

Benign epilepsy with centrotemporal spikes (BECTS) is one of the most common pediatric epileptic syndromes. Recent studies have shown that BECTS can lead to significant language dysfunction. Although research supports the role of the left inferior frontal gyrus (LIFG) in BECTS, it is unclear whether the subregions of the LIFG show different change patterns in patients with this syndrome.

Methods

Using resting-state functional magnetic resonance imaging (fMRI) data in a group of 49 BECTS patients and 49 healthy controls, we investigated whether the BECTS patients show abnormal connectivity patterns of the LIFG subregions.

Results

Compared with healthy controls, the BECTS patients exhibited higher connectivity between the following: the inferior frontal sulcu

SUBMITTER: Yang Y 

PROVIDER: S-EPMC9561512 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature