Computed tomography-based body composition measures in COPD and their association with clinical outcomes: A systematic review.

ABSTRACT:

Background

Computed tomography (CT) is commonly utilized in chronic obstructive pulmonary disease (COPD) for lung cancer screening and emphysema characterization. Computed tomography-morphometric analysis of body composition (muscle mass and adiposity) has gained increased recognition as a marker of disease severity and prognosis. This systematic review aimed to describe the CT-methodology used to assess body composition and identify the association of body composition measures and disease severity, health-related quality of life (HRQL), cardiometabolic risk factors, respiratory exacerbations, and survival in patients with COPD.

Methods

Six databases were searched (inception-September 2021) for studies evaluating adult COPD patients using thoracic or abdominal CT-muscle or a

SUBMITTER: Nicholson JM 

PROVIDER: S-EPMC9561670 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature