White matter tracts involved in subcortical unilateral spatial neglect in subacute stroke.

ABSTRACT:

Background

Unilateral spatial neglect (USN) is common and associated with poor motor and cognitive outcomes as well as impaired quality of life following stroke. Traditionally, the neural substrates underlying USN have been thought to be cortical areas, such as the posterior parietal cortex. However, patients with stroke involving only subcortical structures may also present with USN. While only a few studies have reported on USN in subcortical stroke, the involvement of white matter tracts related to brain networks of visuospatial attention is one possible explanation for subcortical neglect. Therefore, this study aimed to investigate which specific white matter tracts are neural substrates for USN in patients with subcortical stroke.

Methods

Twenty-two patients with subcor

SUBMITTER: Cha S 

PROVIDER: S-EPMC9561922 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature